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Publications

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 Alfred ICU investigators produce peer-reviewed papers regularly.  They also secure millions of dollars in competitive grant funding.

ICU staff are considered key opinion leaders shaping the delivery of patient-centred critical care globally, particularly via online resources (such as intensiveblog.com), which were accessed more than 260,000 times in 2022.

Latest Research Publications -  2022 to 2025

Found 378 research publications
Impact of renin-angiotensin-aldosterone system inhibition on mortality in critically ill COVID-19 patients with pre-existing hypertension: a prospective cohort study

Sato K.; White N.; Fanning J.P.; Obonyo N.; Yamashita M.H; Appadurai V.; Ciullo A; May M.; Worku E.T.; Helms L.; Ohshimo S.; Juzar D.A.; Suen J.Y.; Bassi G.L.; Fraser J.F.; Arora R.C.; COVID-19 Critical Care Consortium Investigators

(2022), BMC CARDIO DISORDERS, 22(123),

DOI: 10.1186/s12872-022-02565-1

Outcomes of patients with refractory out-of-hospital cardiac arrest transported to an ECMO centre compared with transport to non-ECMO centres

Bernard S.A.; Hopkins S.J.; Ball J.C.; Stub D.A.; Stephenson M.W.; Nanjayya V.B.; Pellegrino V.A.; Sheldrake J.; Richardson A.C; Smith K.L.

(2022), CRIT CARE RESUSCIT, 24, 7-13

DOI: 10.51893/2022.1.OA1

The monitoring with advances sensors, transmission and e-resuscitation in traumatic brain injury (MASTER-TBI) collaborative: Bringing data science to the ICU bedside

McNamara R.; Meka S.; Anstey J.; Fatovich D.; Haseler L.; Fitzgerald M.; Udy A.

(2022), CRIT CARE RESUSCIT, 24(1), 39-42

DOI: 10.51893/2022.1.OA5

Physiotherapy-assisted prone or modified prone positioning in ward-based patients with COVID-19: a retrospective cohort study

Claudia Tatlow; Sophie Heywood; Carol Hodgson; Georgina Cunningham; Matthew Conron; Hui Yi Ng; Harry Georgiou; Gemma Pound

(2022), PHYSIOTHERAPY, 114, 47-53

DOI: 10.1016/j.physio.2021.09.001

Six-month outcomes following venovenous ECMO for severe COVID-19 and viral pneumonitis: 2019-2020 Australian experience

Doherty Z.; Kippen R.; Bevan D.; Duke G.; Williams S.; Wilson A.; et al.

(2022), CRIT CARE RESUSCIT,  24 (1), 83-6

DOI: 10.51893/2022.1.OA10

Reply: COVID-19 Is Not Comparable to H1N1 Influenza

Udy, Andrew A.; Bellomo, Rinaldo; Burrell, Aidan JC; Neto, Ary Serpa;

(2022), AMERICAN THORACIC SOCIETY, 19(3), 510-511

DOI: /10.1513/AnnalsATS.202111-1283LE

Association Between Urine Output and Mortality in Critically Ill Patients: A Machine Learning Approach

David Anderson, Luke P. Dawson, Emily Andrew, Ziad Nehme, Jason Bloom, Sinjini Biswas, Shelley Cox, Michael Stephenson, Jeffrey Lefkovits, Andrew J. Taylor, David Kaye, Karen Smith and Dion Stub

(2022), CRIT CARE MED, 50(3), e263-e271

DOI: 10.1097/CCM.0000000000005310

The Global Open Source Severity of Illness Score (GOSSIS)

Raffa J.D.; Johnson A.E.W.; O'Brien Z.; Pollard T.J.; Mark R.G.; Celi L.A.; Pilcher D.; Badawi O.

(2022), CRIT CARE MED, 50(7), 1040-1050

DOI: 10.1097/ccm.0000000000005518

Realising the Potential: leveraging clinical quality registries for real-world clinical research

Susannah Ahern; Belinda J. Gabbe; Sally Green; Carol L. Hodgson; Erica M. Wood; John R. Zalcberg OAM; Tsharni Zazryn

(2022), MJA, 216(6),

DOI: 10.5694/mja2.51443

Ventilation management and outcomes in out-of-hospital cardiac arrest: a protocol for a preplanned secondary analysis of the TTM2 trial

Robba C.; Nielsen N.; Dankiewicz J.; Badenes R.; Battaglini D.; Ball L.; Brunetti I.; Pedro David WG.; Young P.; Eastwood G.; Chew M.S.; Jakobsen J.; Unden J.; Thomas M.; Joannidis M.; Nichol A.; Lundin A.;Hollenberg J.; Lilja G.; Hammond N.E.; Saxena M.; Martin A.; Solar M.;Taccone F.S.;Friberg H.A.; Pelosi P.

(2022), BMJ, 12(3),

DOI: 10.1136/bmjopen-2021-058001

Whole-genome sequencing reveals host factors underlying critical COVID-19

Kousathanas A.; Pairo-Castineira E.; Rawlik K.; Stuckey A.; Odhams C.A.; Walker S.; Russell C.D.; Malinauskas T.; Wu Y.; Millar J.; Shen X.; Elliott KS.; Griffiths F.; Oosthuyzen W.; Morrice K.; Keating S.; Wang B.;, Rhodes D.; Klaric L.; Zechner M.; Parkinson N.; Siddiq A.; Goddard P.; Donovan S.; Maslove D, Nichol A, Semple M.G.; Zainy T, Maleady-Crowe F.; Todd L.' Salehi S.; Knight J.; Elgar G.; Chan G.; Arumugam P.; Patch C.; Rendon A.; Bentley D.;, Kingsley C.; Kosmicki J.A.; Horowitz J.E.; Baras A.; Abecasis G.R.;, Ferreira M.A.R.; Justice A.; Mirshahi T.; Oetjens M.; Rader D.J.; Ritchie M.D.; Verma A.; Fowler T.A.; Shankar-Hari M.; Summers C.; Hinds C.; Horby P.; Ling L.; McAuley D.; Montgomery H.; Openshaw P.J.M.; Elliott P.; Walsh T.; Tenesa A.; GenOMICC Investigators; Fawkes A.; Murphy L.; Rowan K.; Ponting C.P.; Vitart V.; Wilson J.F.; Yang J.; Bretherick A.D.; Scott R.H.; Hendry S.C.; Moutsianas L.; Law A.; Caulfield M.J.; Baillie J.K.

(2022), NATURE, 607(7917), 97-103

DOI: 10.1038/s41586-022-04576-6

Clinical outcomes of Indigenous Australians and New Zealand Maori with metabolic acidosis and acidaemia

Ary Serpa Neto; Tomoko Fujii; James Moore; Paul J. Young; Sandra Peake, Michael Bailey; Carol Hodgson; Alisa M. Higgins; Emily J.; Paul Secombe; Vanessa Russ; Lewis Campbell; Meredith Young; Mikihiro Maeda; David Pilcher; Jamie Cooper; Andrew Udy

(2022), CRIT CARE , 24(1), 14-19

DOI: 10.51893/2022.1.OA2

Protocol summary and statistical analysis plan for Intensive Nutrition Therapy comparEd to usual care iN criTically ill adults (INTENT): a phase II randomised controlled trial

Emma J. Ridley; Michael Bailey; Marianne Chapman; Lee-anne S.; Chapple Adam; M. Deane; Carol Hodgson; Victoria L. King; Andrea Marshall; Eliza G. Miller; S.P. McGuinness; Rachael Parke; Andrew A. Udy

(2022), BMJ OPEN, 12(3),

DOI: 10.1136/bmjopen-2021-050153

Use of an extended KDIGO definition to diagnose acute kidney injury in patients with COVID-19: A multinational study of the ISARIC cohort

Marina Wainstein; Samual MacDonald; Daniel Fryer; Kyle Young; Steven Webb; Husna Begum; Alistair Nichol; James Lee; Valeria Balan; J. Perren Cobb; Aidan Burrell; Kalynn Kennon; Samantha Strudwick; Sadie Kelly; Malcolm G. Semple; Laura Merson; Srinivas Murthy; Barbara Citarella; Patrick Rossignol; Rolando Claure-Del Granado; Sally Shrapnel; The ISARIC Characterization Group

(2022), BMJ YALE, 11(7),

DOI: 10.1101/2022.03.18.22272601

Nutrition Management for Critically Ill Adult Patients Requiring Non-Invasive Ventilation: A Scoping Review

Emma J. Ridley; Elizabeth Viner Smith; Christopher K. Rayner; Lee-Anne S. Chapple

(2022), NUTRIENTS, 14(7), 1446

DOI: 10.3390/nu14071446

Economic evaluations for intensive care unit randomised clinical trials in Australia and New Zealand: Practical recommendations for researchers

Taylor C.B.; Thompson K.J.; Hodgson C.; Liew C.; Litton E.; McGain F. FANZCA; Nichol A.; Rauniyar R. ; Ridley E.; Higgins A.

(2022), AU CRIT CARE, 36(3), 431-437

DOI: 10.1016/j.aucc.2022.02.002

Development of the Consumer Involvement & Engagement Toolkit: a digital resource to build capacity for undertaking patient-centred clinical trials in Australia

Symons T.; Bowden J.; McKenzie A.; Fallon-Ferguson J.M.; Weekes L.Y.; Ansell J. Murphy R.; Jesudason S.; Saxena M.; Nichol A.; Straiton N.

(2022), NEURO ANESTH JOURN, 33(1),

DOI: 10.17061/phrp32122209

An initial Glasgow Coma Scale score of 8 or less does not define severe brain injury

Fitzgerald M.; Tan T.; Rosenfeld J.V.; Noonan M.; Tee J.; Ng E.; Mathew J.; Broderick S.; Kim Y.; Goombridge C.;Udy A.; Mitra B.

(2022), EMERG MED AUSTRALASIA, 34(3), 459-461

DOI: 10.1111/1742-6723.13937

Clinical characteristics, risk factors and outcomes in patients with severe COVID-19 registered in the International Severe Acute Respiratory and Emerging Infection Consortium WHO clinical characterisation protocol: a prospective, multinational, multicentre, observational study

Reyes, Luis Felipe; Murthy, Srinivas; Garcia-Gallo, Esteban; Irvine, Mike; Merson, Laura; Martin-Loeches, Ignacio; Rello, Jordi; Taccone, Fabio S.; Fowler, Robert A.; Docherty, Annemarie B.

(2022), EURO RESPIRATORY SOC, 8(1),

DOI: 10.1183/23120541.00552-2021

A preliminary study of intensivist performed DVT ultrasound screening in trauma ICU patients

Roberts L.; Rozen T.; Murphy D.; Lawler A.; Fitzgerald M.; Gibbs H.; Brooks K.; Ihle J.F.; Leong T.; Orosz J.; Paul E.; Nanjayya V.B.

(2022), ANN INTENSIVE CARE, 14;10(1), 122

DOI: 10.1186/s13613-020-00739-8